Executive Leadership (CEO / CFO)
Portfolio NPV, eNPV, kill-threshold dashboards, and probability-adjusted pipeline value at a glance.
Helix · Pharma Portfolio & Project Management
A real-time command centre for your entire drug pipeline.
A purpose-built platform that gives pharmaceutical and generic drug companies a single, real-time command centre for managing their entire drug development pipeline, from molecule selection to commercial launch.
helix · portfolio
DiscoveryPh IPh IIPh IIIFiled
VX-118
VX-204
VX-330
VX-441
01 The problem
What slows pharma teams down
Generic drug development is one of the most complex coordination challenges in any industry: dozens of departments, hundreds of tasks, multi-market regulatory obligations, and billion-dollar pipeline decisions, yet most organisations still manage it in spreadsheets.
Fragmented pipeline visibility
Molecules, projects, and tasks live in siloed spreadsheets, email threads, and disconnected tools. There's no single source of truth for portfolio status.
Manual risk guesswork
PTRS, business risk, IP, API supply, and KSM assessments are done ad hoc and inconsistently, without a structured scoring framework leadership can trust.
Opaque material & sourcing intelligence
Vendor selection, lead times, country-of-origin risks, and cost benchmarks are buried in procurement files, invisible to R&D and regulatory teams.
Schedule slippage without early warning
Milestone delays cascade silently. By the time leadership sees an overdue submission date, recovery options are limited and costly.
Regulatory complexity overhead
Managing ANDA, Para IV, and 505(b)(2) filing timelines across multiple markets needs real-time cross-team coordination that generic tools can't provide.
No data-driven portfolio prioritisation
Kill / no-kill decisions rely on intuition. Without NPV, eNPV, and risk-adjusted revenue modelling at the portfolio level, resources flow to the wrong molecules.
02 Objectives
What the platform is built to achieve
One north star: give every person in the drug development organisation, from scientist to CEO, the right information at the right time to make better decisions faster.
- 01Give every stakeholder, from bench scientist to CEO, a real-time, role-appropriate view of the entire drug development pipeline.
- 02Standardise and automate five-dimensional risk scoring so every molecule is assessed consistently and comparably.
- 03Surface sourcing risks and material constraints early, before they become supply chain crises.
- 04Eliminate schedule-slippage surprises through milestone tracking, critical path analysis, and proactive alerting.
- 05Enable evidence-based portfolio decisions using NPV, peak revenue, and probability-of-success data in one platform.
- 06Reduce administrative overhead for regulatory teams so they focus on science, not status updates.
03 Our users
Who uses it
The platform serves every role in the drug development and commercialisation lifecycle. Each user gets a role-aware experience, showing exactly what they need without the noise of information meant for other functions.
Portfolio Manager / PMO Lead
Cross-portfolio dashboard, resource allocation, milestone roll-up, and executive reporting.
VP Regulatory Affairs
Filing timeline management, dossier milestone tracking, and multi-market status across ANDA, Para IV, and 505(b)(2) submissions.
VP Formulation R&D
Prototype-to-exhibit batch progress, formulation risk flags, and team task assignments across concurrent molecules.
VP Analytical Development
Method development and validation milestones, dissolution study timelines, and cross-molecule analytical workload.
VP Quality Assurance
Stability program status, batch release gating, QA sign-off workflows, and audit-readiness metrics.
Supply Chain / Manufacturing Lead
KSM and CRM vendor qualification status, API lead times, geographic concentration risk, and commercial-scale readiness.
Commercial / Business Analyst
Market size, revenue-at-launch forecasts, peak revenue, and market launch readiness reports.
Scientist / Formulation Researcher
Personal task list, phase milestone dates, document uploads, and real-time status on their molecules.
04 Capabilities
What the platform can do
Six integrated capability areas cover the full scope of pharma portfolio and project management, working together as one platform, not a collection of disconnected tools.
Portfolio & Program Management
Organise your entire drug development pipeline into portfolios, programs, and molecules. Track status, ownership, market, and commercial metrics in one consolidated view, and drill from executive summary to molecule-level detail in seconds.
Molecule Lifecycle Management
Manage every molecule through its development lifecycle, from feasibility to commercial launch. Define phase milestones, track actual vs. planned dates, capture hold reasons, and monitor the critical path across the portfolio.
Five-Dimensional Risk Intelligence Engine
Score and monitor risk across five independent dimensions: PTRS (Technical Probability of Success), Business Risk, IP & Patent Risk, API Supply Risk, and KSM (Key Starting Material) Risk. Every assessment is structured, scored, and auditable.
Material & Sourcing Intelligence
Capture and track KSM, CRM, and advanced intermediate materials per molecule. Evaluate vendors by price, lead time, country of origin, and geographic concentration risk, and align sourcing with regulatory and supply chain strategy.
Project Planning & Gantt Scheduling
Build detailed project plans with workstreams, milestones, and task-level assignments. Visualise timelines on interactive Gantt charts, flag critical path items, and track completion status in real time.
Analytics, NPV & Executive Reporting
Model NPV and eNPV at the molecule level using market size, revenue-at-launch, and probability of success. Generate portfolio analytics, cluster reports, and functional performance dashboards.
05 The foundation
Enterprise-grade, built for trust
The platform is engineered for the realities of regulated work: secure, auditable, and ready to scale and connect with the systems you already rely on.
Secure and access-controlled
Role-based access and tenant data isolation, so the right people see the right data and nothing more.
Audit-ready by design
Built for pharma-grade data integrity and traceability. Every change is logged and ready for review.
Scales with your portfolio
A modern cloud foundation that grows from a handful of molecules to your entire global pipeline.
Fits your existing systems
Open APIs connect to the tools you already run, from ERP and LIMS to regulatory and BI platforms. Private, governed AI assists with risk scoring without taking the decision out of your hands.
Built by practitioners who understand the complexity of generic drug development. Every feature exists because a real team needed it, and every data point is designed to support a real decision.